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GLP-1-induced nausea results from delayed gastric emptying and direct receptor activation in the brainstems area postrema not oxidative stress

Disclaimer Not Evaluated by the FDA These statements have not been evaluated by the Food and Drug Administration, and sermorelin is not FDA-approved to diagnose, treat, cure, or prevent any condition outside of recognized uses

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For example, gut microbiota-derived indole-3-acetic acid (3-IAA), a tryptophan metabolite, accumulates in the TME and is oxidized by neutrophil myeloperoxidase (MPO), generating a burst of ROS