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Notably, treatments with the multi-agonists or GLP1 did not cause signs of nausea/malaise at any time-point tested (272 h), since pica behavior (i.e., kaolin intake) was similar, or even lower, in mice treated with GLP1/E, GLP1/GIP, GLP1/GIP/Glucagon, or GLP1 vs
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This way, you support your body in both ways: direct intake and endogenous production
In a further set of experiments, IBMX (at a higher dose) was added only for the final 10 min out of the 16 h incubation for a point estimate of cAMP synthesis rate
PubMed Babiker R, Merghani TH, Elmusharaf K, et al
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