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Anti-Fibrotic and Scar Reduction Activity : The Klow Blend modulates TGF- signaling to minimize fibrosis and excessive scar formation
K.ChouM
Allantoin: Calms and soothes irritated skin, promoting repair
In the most immediate period after injury induction (skin defect) (i.e., 2, 5, and 10 min), BPC 157 increases Akt1, Braf, Egfr, Egr1, Grb2, Hdac7, Kras, Mapk1, Mapk3, Mapk14, Nos3, Pik3cd, Plcg1, Prkcg, Ptk2, Pxn, Src, Srf, and Vegfa gene expression in rats excision wounds in the skin
At higher doses, some concern exists about pro-inflammatory effects: LL-37 can activate NF-kB pathways, potentially worsening certain inflammatory conditions
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