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Seiwerth S, Rucman R, Turkovic B, Sever M, Klicek R, Radic B, Drmic D, Stupnisek M, Misic M, Vuletic LB, Pavlov KH, Barisic I, Kokot A, Japjec M, Blagaic AB, Tvrdeic A, Rokotov DS, Vrcic H, Staresinic M, Sebecic B, Sikiric P
Despite best efforts with the Universal Definition, slight variance in definition may influence collection of outcome and clinical data
2.5 Model Predictions Because of substantial log-normal within-individual variability, standard computation of reference subject simulations, as well as population predictions and weighted residuals reported by the nonlinear mixed-effects modelling software (NONMEM) are poor measures to reflect data
doi: 10.5056/jnm.2011.17.2.105
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