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Mechanisms of Action: AOD-9604: Modified fragment of human growth hormone (176191) that triggers fat metabolism without affecting blood sugar or growth factors
Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure
However, as human erythrocytes are nucleus- and organelle-free cells, the effects of erythrocytic ceramides should be restricted to the plasma membrane and plasma membrane-associated proteins
This article was supported by Novo Nordisk Inc., who performed a medical accuracy review
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