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N Engl J Med 2020;383:2219-29.ArticlePubMed 130

Alcohol reduction is advisable

Oral medications have peaks and valleys with mostly subtherapeutic levels between doses

The DAC version has an albumin-binding tail that extends its half-life to roughly 6 to 8 days, producing a sustained, non-pulsatile elevation of GH and IGF-1