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Similarly, the STEP UP Obesity trial revealed that about 33% of patients on the 7.2 mg dose lost 25% or more of their starting weight, while only 15% of those on the lower dose achieved the same level of weight loss

Reported Sex-Based Variability in the Literature Where sex-based data does appear, researchers generally attribute observed variability to differences in baseline endogenous IGF-1 and growth hormone signaling between male and female physiology, rather than to any fundamental difference in how IGF-1 LR3 binds or activates the IGF-1 receptor

It has neuro-protective and neuro-enhancing effects, and research has indicated benefits in various neurological and cognitive conditions