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XOR appears to have a dichotomous role in tumor biology: XOR products are associated with both induced mutagenesis and cell proliferation, as well as with cell differentiation and apoptosis (399)

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5 days) significantly reduces the senescence level in PDL9 cells [2]

Immunohistochemical analysis of biopsy and postmortem samples revealed increased expression of UPR markers, including CHOP and BiP, in oligodendrocytes, astrocytes, T cells, and macrophages/microglia within MS lesions