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Proc Natl Acad Sci U S A 99:14916, PMID: 11792859 Ishii T, Hishinuma I, Bannai S, Sugita Y (1981) Mechanism of growth promotion of mouse lymphoma L1210 cells in vitro by feeder layer or 2-mercaptoethanol
Improves kidney function and can reverse anemia
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Cystinosin deficiency leads to impaired lysosomal clearance and disrupted endolysosomal trafficking, which in turn contributes to defective autophagy and altered proteostasis [144, 146, 147]
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