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Clinical guidance advises raising the dose slowly when nausea is present, and notes that persistent vomiting or diarrhea can lead to dehydration and even kidney strain, per the GLP-1 receptor agonist review on the NCBI Bookshelf
You abuse nitrous oxide (laughing gas)
Eating bland foods, staying hydrated, and consuming smaller meals can help alleviate nausea
True pharmaceutical transdermal GLP-1 delivery systems are in early research stages
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