It was a 12-month, randomized, placebo-controlled, double-blinded study enrolling 131 postmenopausal women with reduced bone mineral density (DXA T-scores of -1 or lower at either the femoral neck or lumbar spine)
There is no rigid dosing protocol- everyone is a different case and is treated as such
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Most of them exert redox potential control and oxidoreductase function, e.g., glutathione peroxidase (GPX/GPx) 14 and 6, thioredoxin reductase (TXNRD/TrxR) 13, and selenoprotein R/methionine sulfoxide reductase B1 (SELENOR/SelR/MSRB1)
Lastly, keep in mind that most studies showing efficacy of GLP-1 agonists for weight loss usually require participants to make lifestyle modifications such as changes in diet and exercise, to control portions and eat high nutrient, low energy foods and move more while taking the medications