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Titration: There is generally no need for upward titration with B-complex vitamins as one might do with certain drugs, but if a patient is frail or known to react to injections, the provider may choose to start at a lower dose (for example 0.25-0.5 mL) and then increase to 1 mL as tolerated
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Certain people are at greater risk for deficiency because of things like diet, lifestyle, and prescription medications
In the case of vitamin B 12 there is no UL, as there is no human data for adverse effects from high doses
human and veterinary use are excluded
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