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This can lead to weight cycling, which has been shown to cause fluctuations in cardiovascular risk factors, such as blood pressure, heart rate, sympathetic activity, and circulating levels of glucose, lipids and insulin
GIP receptor activation also appears to have independent effects on fat metabolism and energy expenditure
Some patients or prescribers may be tempted to accelerate this process, but doing so often leads to intolerable nausea and vomiting, potentially causing treatment discontinuation before therapeutic doses are reached
If you miss a day and it has been less than 5 days since the missed dose, take it as soon as you remember
MASH resolution index: development and validation of a non-invasive score to detect histological resolution of MASH
