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This perspective, while understandable from a historical context, conflicts with current American Medical Association guidelines that recognize obesity as a chronic disease requiring multimodal treatment including pharmacotherapy when appropriate

52,53 In addition, cinchonine can inhibit toll-like receptor 2- (TLR2-) and TLR4-mediated signaling cascades, and attenuate pro-inflammatory cytokine levels in high-fat diet-induced obesity mice

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Xiang J, Ding XY, Zhang W, Zhang J, Zhang YS, Li ZM, et al