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Freezing reconstituted peptides is generally discouraged as the formation of ice crystals can damage the peptide structure

Neuron 2:154758, PMID: 2576375 Juurlink BH (1997) Response of glial cells to ischemia: roles of reactive oxygen species and glutathione

However, the combined administration of these anticancer drugs and mesna leads to increased urinary excretion of cysteine, GSH, and homocysteine (Pendyala et al., 2000)

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Different testing methods are used to test for toxicity because each toxin is excreted differently