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In the current HepG2 cell model, in which prolonged exposure is not feasible, the use of relatively high QI concentrations in a short timeframe allows for the identification of underlying mechanisms and pathways, as has been done previously in similar studies with hepatic toxicants (Tafazoli and OBrien, 2009

Consistent with the ATF4-mediated transcriptional control for GSH biosynthesis, these cells all showed higher levels of GSH and the lack of replication stress

Topical steroids dangerously thin out the skin

The amino acids lysine and methionine are converted to L-Carnitine in the body by the liver and kidneys

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