So the case for oral options isnt that injections are bad its optionality
resolve with titration.[1][43] Absolute Contraindications : History of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2.[3][44] Relative Contraindications : Pancreatitis, severe GI disease, pregnancy/breastfeeding.[1][45] Monitoring Parameters : HbA1c, lipids, liver enzymes, renal function every 3 months.[4][46] Regulatory Status FDA Classification : Investigational (Phase 3)
Then, every four weeks, they will gradually increase your dosage until you reach the maximum effective dosage for you ( 1.7 mg or 2.4 mg weekly)
Pyrroloquinoline quinone ameliorates renal fibrosis in diabetic nephropathy by inhibiting the pyroptosis pathway in C57BL/6 mice and human kidney 2 cells
They should be prescribed in the context of a patients medical history, symptoms, contraindications, and follow-up needs