M., Denk, F
National Law Review (Polsinelli PC) was explicit on April 22, 2026: removing a Category 2 bulk drug substance does not, on its own, authorize use of that substance in compounding or bring it within FDAs interim enforcement discretion policy for substances in Category 1. Even Category 1 substances are only under enforcement discretion, which is short of full authorization
Kubo Y, Tanaka K, Masuike Y, Takahashi T, Yamashita K, Makino T, et al
Typical timeline observed with daily oral use: 24 weeks: Improved hydration and subtle glow 68 weeks: Early brightening and smoother tone 812 weeks: Visible pigmentation softening 36 months: Stable and noticeable tone balance Because skin renews itself approximately every 2840 days, visible results take time
Journal of Parenteral and Enteral Nutrition, 36 (2), 147154