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For this axis, relevant endpoints include phosphorylation of anabolic signaling intermediates, expression of muscle-regulatory genes, satellite cell activity, and indices of protein accretion or repair
Some studies show weight loss and small A1c improvements in certain people, often those with overweight or obesity, but nausea and tolerability are common issues
This is often due to a drop in testosterone levels, which can occur naturally with aging or as a side effect of certain medical treatments, such as those for prostate cancer
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