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Survodutide (BI 456906) is similar to the active ingredient tirzepatide (Mounjaro, Zepbound) in that it combines two mechanisms of action
This is especially true when introducing glutathione supplement, as they can potentially lead to irritability
Zhang J, Liu C, Liao Y, He W, Zheng Y, Shi H, Liu Q, Lin J, Gao C, Wang X, Gao L (2026) Copper overload induces lifespan shortening through activating mitochondrial respiration in Caenorhabditis elegans
PMID 17186181
10.1006/bbrc.1995.1106 Summary Keywords ketosteroid isomerase, androstenedione, progesterone, ecdysteroid, glutathione, steroid hormone, enzyme evolution, alternative functions Citation Mannervik B, Ismail A, Lindstrm H, Sjdin B and Ing NH (2021) Glutathione Transferases as Efficient Ketosteroid Isomerases
