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The dose is increased stepwise according to your response and tolerance: Weeks 58: 0.5 mg weekly Weeks 912: 1.0 mg weekly Weeks 1316: 1.7 mg weekly Week 17 onwards: 2.4 mg weekly (maintenance dose) Your doctor will tailor this schedule to your unique medical history and progress
Monotherapy with RYBELSUS 7 mg and RYBELSUS 14 mg once daily for 26 weeks resulted in a statistically significant reduction in HbA1c compared with placebo (see Table 4)
Potthoff MJ, Potts A, He T, Duarte JAG, Taussig R, Mangelsdorf DJ, et al
The GLP-1 hormone also slows digestion, inhibits the release of glucagon (another hormone that regulates blood glucose), and helps signal to your brain when youve had enough to eat
GLP-1 and exendin-4 show a similar nM affinity while glucagon, secretin, VIP and GLP-2 have at least a hundred times lower affinity for the GLP-1 receptor
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