doi: 10.1097/PAS.0000000000000398 79 HaywardNKWilmottJSWaddellNJohanssonPAFieldMANonesKet al
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Reconstitution steps: Allow vial to reach room temperature before opening Wipe rubber stopper with an alcohol swab and allow to dry Insert needle bevel-up at a 45 angle through the stopper Inject bacteriostatic water slowly along the glass wall, do not aim at the lyophilised cake Gently swirl until fully dissolved, do not vortex, shake, or sonicate Inspect for clarity and absence of particles before use Storage: Lyophilised vials (store at 20C, protected from light)
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Semaglutide, available as Ozempic for type 2 diabetes and Wegovy for chronic weight management, and tirzepatide, marketed as Mounjaro for type 2 diabetes and Zepbound for weight management, are prominent examples of FDA-approved GLP-1 receptor agonists (Kommu S et al., 2025