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When this system is inhibited, GSH synthesis declines, leading to inactivation of GPX4

With B12 deficiency becoming common so is supplementing through B12 injections

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By contrast, many traditional drugs affect several parts of a biological system at once I call it carpet-bombing the whole system

Within the context of the GABA shunt 2-oxoglutarate (-ketoglutarate) is transaminated to the amino acid glutamate by GABA -oxoglutarate transaminase (GABA-T)