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Development of new nevi (moles) and changes to pre-existing ones Several researchers have documented cases where MT-II administration caused the development of new pigmented nevi or pre-existing nevi to grow and darken in color
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This defense can include the release of inflammatory molecules, such as cytokines and chemokines, and the recruitment of immune cells to the site of the injection
In patients with Neurofibromatosis type 1 (NF1), malignant transformation of a pre-existing plexiform neurofibroma may be indicated by a sudden increase in size, new-onset pain, or neurologic deficits
