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The pituitary gland releases GH in pulses, and that release is gated by two independent controls: a go signal from GHRH and a separate go signal from the ghrelin/GH-secretagogue receptor

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The peptides can also improve bone health and cognitive function

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This can be accomplished through the utilization of various pharmacological agents, such as DPP-4 inhibitors, SGLT2 inhibitors, insulin, glucagon-like peptide-1 (GLP-1) receptor agonists, and metformin (106)

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