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This higher maximum dose provides greater reductions in body weight (6.9kgs vs 6.0kgs) and A1c (2.2 vs 1.9% ) when compared to 1.0 semaglutide dose

The Medical Necessity Clause: Just because a drug is on the formulary doesn't guarantee coverage

It is worth noting that our participants had a higher baseline BMI (mean 41.5 kg m 2 ) than in the STEP 1 trial (37.9 kg m 2 ), with some studies 24 showing that greater weight loss is observed with a higher baseline BMI, which may explain the greater %WL observed in our trial

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