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Lesions of the central auditory pathway may play a significant role in the development of ARHL in addition to those that affect the peripheral auditory system [7]

At higher supplemental doses (500 to 3000 mg daily), niacinamide can cause nausea, liver enzyme elevation, or glucose intolerance, but these effects are unlikely at the low doses used in compounded formulations

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After Treatment: Resume normal activities immediately

We identified six biophysical properties that can be predicted from a sequence using the ProtParam module ( from the biopython Python package 45 : (1) the isoelectric point in neutral pH, (2) GRAVY (grand average of hydropathy) 46 , (3) the instability index 47 , (4) aromaticity, (5) the molar extinction coefficient and (6) molecular weight