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This means its effectiveness and safety for people remain unproven, making any use a significant gamble

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In addition to weight loss, semaglutide has also been associated with other health benefits

The researchers found that turning off GLP-1 in the brain didnt affect the normal daily intake of food, but instead was important in several specific situations: prolonged fasting, large feedings, and stress-induced appetite loss.[ref] Controlling binging, regulating satiety: Essentially, the neurons activated by GLP-1 help to limit binging after a fast they keep you from massively overeating after not eating for a while

Insulin-PI3K signalling: an evolutionarily insulated metabolic driver of cancer