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Some dialysis patients may be candidates for GLP-1 medications, while others may not tolerate them well

74 Exenatide therapy was associated with lower cardiac enzyme values during the first 72 hours and a reduction in infarct size according to cardiac MRI at 1 month compared with placebo

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In order to lower high blood glucose levels, glibenclamide stimulates the pancreas to release more insulin

So patients will be eligible for the bridge if they have a BMI of 35 or higher, a BMI of 30 or higher with uncontrolled hypertension, chronic kidney disease stage 3A or above, or heart failure with preserved ejection fraction