Free radicals are unstable molecules that damage cell membranes, proteins, and DNA, and antioxidants like glutathione are how the body keeps that damage in check
Such differences suggest reduced CBS activity in the transsulfuration pathway and lower H 2 S production by this enzyme in mother and placental-fetal unit in severe IPTB cases
New Phytol 208:860872 Kovacs I, Holzmeister C, Wirtz M, Geerlof A, Frhlich T, Rmling G, Kuruthukulangarakoola GT, Linster E, Hell R, Arnold GJ, Durner J, Lindermayr C (2016) ROS-mediated inhibition of S-nitrosoglutathione reductase contributes to the activation of antioxidative mechanisms
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Schloesser, D