In contrast, the arginase pathway, which breaks down arginine and thus reduces NO production, is highly expressed in M2 macrophages
If it is shown that such violations were committed with the intent to defraud or mislead, penalties can be increased to imprisonment for up to three years and fines of $10,000 per violation

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Diabetes Metab Res Rev 2025;41:e70037.PubMedPMC 81
Without coverage, list price runs high, over $1,000 monthly for either medication