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Diabetes: Hyperglycaemia causes increased free radical production which uses up glutathione stores

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Nitric oxide stimulates growth hormone secretion from human fetal pituitaries and cultured pituitary adenomas

Tendon and Ligament Repair Moderate to Strong Evidence Evidence Rating: Moderate-Strong (Several animal studies, some independent replication) Research support for musculoskeletal healing is substantial: Achilles tendon injuries Ligament damage (MCL, ACL) Rotator cuff healing General tendinopathy Surgical repair enhancement The FAK-paxillin mechanism and VEGF upregulation provide clear biological rationale for these effects

They face a higher risk of B12 deficiency