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Aquatic Toxicol 101:1330 Belrose JC, Xie YF, Gierszewski LJ, MacDonald JF, Jackson MF (2012) Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons
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This delayed gastric emptying is particularly important for glycemic control and weight reduction, as it prolongs the sensation of fullness and reduces postprandial glucose excursions
2 Design logic of multifunctional nanotherapies targeting the tumor microenvironment 2.1 Key tumor microenvironmental barriers and corresponding design objectives The tumor microenvironment features that shape drug delivery and therapeutic response in solid tumors can be grouped into three levels that are particularly relevant for nanomedicine design, namely the vasculature and interstitium, the extracellular matrix, and the immune compartment [29,30,31]
