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BPC-157 is a relatively small peptide (molecular weight approximately 1,419 Da), and its stability against proteolytic degradation has been noted in vitro, but whether it reaches the liver in sufficient concentration to affect CYP activity is unknown
As such, its structural composition is unique compared with other FcRn antagonists, as it mimics the natural Fc:FcRn interaction rather than blocking the Fc binding site on FcRn by an antigen:Fab interaction
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This metabolite demonstrates anti-fibrotic properties across multiple organ systems [9]
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