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The vagus nerve provides the gastrointestinal tract, pancreas, and liver parasympathetic innervation (Fox and Powley 1985) (Fig
Physiology, Gluconeogenesis
While most popularly known for diabetic treatment and weight loss, early trials suggest this class of medicines may also be a way to break addictions to substances like opioids
In contrast to other DPP-4 inhibitors, linagliptin does not require dose adjustment in patients with renal insufficiency given that it is not excreted by the kidneys [15]
However, misuse or improper dosing can lead to side effects, including joint pain, water retention, or hormonal imbalances
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