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Liver detoxification is more accurately called biotransformation and elimination
UK guidelines recommend monitoring clinical response and full blood count (typically at around 2 months) to ensure treatment adequacy, rather than routinely rechecking B12 levels after replacement has started
10.1074/jbc.M112.395541 43 GrefenC.DonaldN.HashimotoK.KudlaJ.SchumacherK.BlattM
International Journal of Molecular Sciences, 19 (7), 1987
That introduces measurement error
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