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Thielen, N

This is one reason the FDA specifically warns against doses closer than 72 hours

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Existing GLP1R agonists come with boxed warnings of thyroid cancer and pancreatitis, based mainly on rodent studies, where the effects of GLP1R agonism have noted species differences (For example, weight loss in rodents is mainly due to increased energy expenditure, whereas in humans it occurs via less food intake [54] )

I've continued to microdose, at an even lower dose once I lost the weight