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Perhaps the closest he comes to this consideration might be his mention of nostril dilation in fearful horses, but he argues that this is the result of an association between fear and the exertions of rapid flight (Darwin, Reference Darwin1872: 130), rather than functioning to detect a source of danger

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10.1016/j.jaim.2016.12.004 242

Most patients begin noticing significant improvement within the first two to four weeks