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References Heffernan M, et al
[73] As noted above, the completely synthetic laboratory synthesis of B 12 was achieved by Robert Burns Woodward and Albert Eschenmoser in 1972, though this process has no commercial potential, requiring more than 70 steps and having a yield well below 0.01%
Monitor blood glucose closely if using MK-677, which can raise fasting glucose by 5 to 15 mg/dL
[114] This functionality is lost in vitamin B 12 deficiency, and can be measured clinically as an increased serum methylmalonic acid (MMA) concentration
Fast Facts B12 is a nutrient needed to form red blood cells, DNA, and brain and nerve cells
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