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Clinical trials use strict protocols, monitor patients closely, and exclude people with severe pre-existing GERD

The Therapeutic Goods Administration (TGA) in Australia has been working with Novo Nordisk, pharmaceutical wholesalers and organisations representing health professionals and patient groups to manage the current shortage

Carnosine is found throughout the body, but specifically in skeletal muscle

An important point is that the control of mood and energy homeostasis often uses overlapping brain circuits (30)

the magnitude of HbA1c change in this non-diabetic population was modest, as would be expected Fasting insulin levels decreased, indicating improved insulin sensitivity Triglyceride and lipid profiles showed favourable changes, which may reduce cardiometabolic risk Waist circumference was substantially reduced, reflecting a decrease in visceral (abdominal) adiposity These findings are particularly relevant given that excess visceral fat is strongly associated with type 2 diabetes, cardiovascular disease, and metabolic syndrome