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Clinically, reserpine is primarily of historical importance , although it is available for use in patients with resistant hypertension, and has been used for many years in animal experiments to deplete catecholamine levels
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At standard dosages (1 to 2 mg per day), the risk is negligible
(2) Increased acetylcholine stimulates muscarinic M3 receptors on the ciliary muscle, producing ciliary muscle contraction
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