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Feedback: Pyruvate is reduced to lactate when cytoplasmic NADH accumulates, for example during normal anaerobic respiration

The PKA and EPAC2 pathways are triggered by both receptors'activation of adenylate cyclase, which raises intracellular cAMP and causes insulin synthesis and release, cellular proliferation, and antiapoptotic effects

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Dimensions: 15.3 in. x 6.1 in. x 11.2 in. (39 cm x 15.4 cm x 28.4 cm), head horizontal

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