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Ideal candidates are typically adults struggling with their weight who have not found success with diet and exercise alone
The approval happened after participants in several GLP-1 trials experienced significant reductions in major cardiac crises, such as heart attacks and strokes, and fewer cardiovascular deaths, says Isaacs
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GLP-1 receptors influence the gut-brain axis
But an in-vitro permeability score is not the same as a measured oral bioavailability figure in an animal, and it is certainly not evidence of a human effect
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