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Mistake 5: not accounting for dead space Every syringe has "dead space" in the hub where a small amount of medication remains after the plunger is fully depressed
Together, they address repair from two different biological angles
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Interestingly, the obese MCAS patients tolerated the high dose quite well, while others did fine on lower doses
In the open-label lead-in phase, patients received a once-weekly subcutaneous injection of tirzepatide for 36 weeks
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