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For people with genuine B12 deficiency or suboptimal levels, supplemental B12 can meaningfully improve energy levels, mental clarity, and exercise tolerance
Individuals with neuromuscular disorders such as ALS or myasthenia gravis are also recommended against treatment with neuromodulators like Botox as it may exacerbate these conditions
No controlled trial has tested this schedule or established when skin changes should appear and while reports on public forums are extensive, each individual may respond differently
The efficient depletion of gut microbiota after antibiotic treatment was confirmed by detection of bacterial 16S DNA (Supplemental Figure 1C)
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