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Molecules 23 , 3283 (2018)

In 51 females and nine males having a body mass index (BMI) between 27 and 39 kg/m2, relationships between serum IGF-1, IGF-binding protein-3 (IGFBP-3), insulin, growth hormone (GH), blood glucose, and anthropometric measurements of body fat were examined

Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with type 2 diabetes (LEAD-1 SU)

This is a theoretical concern and not a commonly reported clinical side effect with standard doses

Potential measurements include: Reactive oxygen species Lipid-peroxidation markers Protein-oxidation markers DNA-damage variables Antioxidant-enzyme expression Redox-sensitive signaling Mitochondrial measurements Cell viability A reduction in one oxidative marker does not establish antioxidant protection or a health benefit