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The reasons are multifactorial: chronic inflammation damages blood vessel walls, corticosteroid use raises cholesterol and blood pressure, lupus-specific antibodies (particularly antiphospholipid antibodies) increase clotting risk, and the metabolic disruption caused by both the disease and its treatments creates a perfect storm for atherosclerosis

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April 5 Product: Bristol Myers Squibb and 2seventy Bios Abecma Indication: Multiple myeloma Early Friday, the FDA handed Bristol Myers Squibb and 2seventy Bio a long-awaited approval for their CAR-T therapy Abecma in third line multiple myeloma

However, this can lead to increased blood flow, better oxygen and nutrient delivery in the tissues

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