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For specific applications such as preventing chemotherapy-induced toxicity, a dose of 1.5 g/m may be administered over approximately 15 minutes, according to Dr
Furthermore, the redox activity of PDI, but not its chaperone function, rescued motor dysfunction and axonopathy in zebrafish models of ALS expressing mutant SOD1, together implying that PDI has an important role both in vitro and in vivo (Parakh et al., 2020)
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