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In animal studies, the most-cited pathways are the nitric-oxide (NO) system and VEGF-mediated angiogenic signaling (Seiwerth et al., 2014
& Jones, A.W
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Selenium and immune function: A systematic review and meta-analysis of experimental human studies
Most of the published lab work studies GHK-Cu effects on dermal fibroblasts specifically, though less research exists on fibroblasts from cardiac, lung, or joint tissue
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