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Kanjwal K, Jamal S, Kichloo A, Grubb BP

The study demonstrated that HIF-3 exists as multiple isoforms with distinct structural and functional properties, some of which act as negative regulators of hypoxia signaling by competing with HIF-1 and HIF-2 for DNA binding or dimerization with HIF-

Contraction-mediated injury represents a major pathological contributor to progressive muscle degeneration in muscular dystrophy, making therapies that attenuate this type of damage clinically relevant

PMID 16746266

Studies in fast-aging XpdTTD/TTD mouse models reveal comprehensive rejuvenation effects following FOXO4-DRI administration